Somali National Army (SNA) troops took control of the road during the ongoing operation against militants in Hiiraan region.
The road connects Bulburde and Beledywene districts in Hiiraan.
Al-Shabaab militants have been in complete control of the road since 2009.
On Wednesday, SNA forces cleared the road of any remaining presence of Al-Shabaab militants with the support of locals.
Senior SNA officers confirmed the latest development to state media.